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Cardiotrophin 1 Protein (CTF1)

This Recombinant Cardiotrophin 1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7482110
发货至: 中国
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Quick Overview for Cardiotrophin 1 Protein (CTF1) (ABIN7482110)

抗原

See all Cardiotrophin 1 (CTF1) 蛋白
Cardiotrophin 1 (CTF1)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 9
  • 5
  • 4

资源

  • 13
  • 2
  • 2
  • 1
大肠杆菌(E. Coli)

应用范围

Western Blotting (WB), Cell Culture (CC)

纯度

≥98 % (HPLC)
  • 原理

    Recombinant human Cardiotrophin-1 protein

    序列

    SRREGSLEDP QTDSSVSLLP HLEAKIRQTH SLAHLLTKYA EQLLQEYVQL QGDPFGLPSF SPPRLPVAGL SAPAPSHAGL PVHERLRLDA AALAALPPLL DAVCRRQAEL NPRAPRLLRR LEDAARQARA LGAAVEALLA ALGAANRGPR AEPPAATASA ASATGVFPAK VLGLRVCGLY REWLSRTEGD LGQLLPGGSA

    特异性

    Toxin target: Leukemia Inhibitory Factor (LIF) receptor, ILST/gp130 receptors

    内毒素水平

    <0.1 EU per 1 μg of the protein by the LAL method.

    Biological Activity Comment

    Cardiotrophin-1 is a member of the neuropoietic cytokine family which enhances the survival of ciliary and dopaminergic neurons through the interaction with the gp130 receptor. Cardiotrophin-1 induces cardiac myocyte hypertrophy and has been shown to promote the survival of both embryonic and neonatal rat ventricular muscle cells1-3.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
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    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 应用备注

    Antigen Preadsorption Control: 10 - 100 nM

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. Reconstitute in sterile, high-purity water at a concentration of at least 0.1 mg/mL. For long-term storage, aliquot the solution into small, single-use vials and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. For storage of dilute working solutions, we recommend adding a carrier protein (e.g., 0.1 % BSA) to your buffer to prevent material loss due to protein adsorption. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.

    缓冲液

    Lyophilized from sterile double distilled water (ddH2O).

    注意事项

    Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture

    储存条件

    -20 °C

    储存方法

    The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.
  • 抗原

    Cardiotrophin 1 (CTF1)

    别名

    Cardiotrophin-1

    背景

    A recombinant human cytokine that promotes cardiac myocyte hypertrophy and survival, and acts as a neurotrophic factor via the gp130/LIFR receptor complex

    分子量

    21.1 kDa

    UniProt

    Q16619

    途径

    JAK/STAT Signaling
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