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LGR6 蛋白

This Synthetic Nanodisc LGR6 protein is expressed in HEK-293 Cells.
产品编号 ABIN7491691
发货至: 中国

Quick Overview for LGR6 蛋白 (ABIN7491691)

抗原

See all LGR6 蛋白
LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

蛋白类型

Synthetic Nanodisc

宿主

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资源

  • 3
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HEK-293 Cells
  • 原理

    Human LGR6 full length protein-synthetic nanodisc

    产品特性

    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

    别名

    LGR6

    背景

    The protein is a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding.

    分子量

    The human full length LGR6 protein has a MW of 104.3 kDa

    UniProt

    Q9HBX8
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