TSH receptor 蛋白
Our Local Distributor
北京 101111
Quick Overview for TSH receptor 蛋白 (ABIN7491755)
抗原
See all TSH receptor (TSHR) 蛋白蛋白类型
宿主
资源
-
-
原理
- Human TSHR full length protein-synthetic nanodisc
-
产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
-
-
Thyroid Stimulating Hormone Receptor (TSHR) (AA 22-260) protein (His tag)
TSHR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Thyroid Stimulating Hormone Receptor (TSHR) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)TSHR 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
说明
-
Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
-
别名
- TSHR
-
背景
- The protein is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism.
-
分子量
- The human full length TSHR protein has a MW of 86.8 kDa
-
UniProt
- P16473
-
途径
- Thyroid Hormone Synthesis
抗原
-
