CCL16 蛋白
Our Local Distributor
北京 101111
Quick Overview for CCL16 蛋白 (ABIN7455689)
抗原
See all CCL16 蛋白蛋白类型
宿主
资源
纯度
-
-
原理
- Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed.
-
产品特性
- Extracellular Domain Protein
-
纯化方法
- Affinity purification
-
-
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His-IF2DI Tag)
CCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)CCL16 宿主: 人 宿主: Yeast (Pichia pastoris) Recombinant > 95 % SDS, WB, ELISA, IP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His-SUMO Tag)CCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
-
别名
- CCL16
-
背景
- CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30 % sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
-
分子量
- 11 KDa
-
UniProt
- O15467
抗原
-
