IL-2 Protein (His tag)
Quick Overview for IL-2 Protein (His tag) (ABIN7455647)
抗原
See all IL-2 (IL2) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This IL-2 protein is labelled with His tag.
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原理
- Recombinant Human Interleukin-2 Superkine is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F) is expressed with a 6His tag at the C-terminus.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- IL-2 (IL2) (Interleukin 2 (IL2))
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别名
- IL-2
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背景
- Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.
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分子量
- 16.5 KDa
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UniProt
- P60568
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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