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IL-2 Protein (His tag)

This Recombinant IL-2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7455647
发货至: 中国

Quick Overview for IL-2 Protein (His tag) (ABIN7455647)

抗原

See all IL-2 (IL2) 蛋白
IL-2 (IL2) (Interleukin 2 (IL2))

蛋白类型

Recombinant

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HEK-293 Cells

纯度

Greater than 95 % as determined by reducing SDS-PAGE.
  • 标记

    This IL-2 protein is labelled with His tag.

    原理

    Recombinant Human Interleukin-2 Superkine is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F) is expressed with a 6His tag at the C-terminus.

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.

    分子量

    16.5 KDa

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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