PDGF-BB Homodimer 蛋白
Our Local Distributor
北京 101111
Quick Overview for PDGF-BB Homodimer 蛋白 (ABIN7455626)
抗原
蛋白类型
宿主
资源
纯度
-
-
原理
- Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
-
产品特性
- Extracellular Domain Protein
-
纯化方法
- Affinity purification
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- PDGF-BB Homodimer
-
别名
- PDGF-BB
-
背景
- Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
-
分子量
- 12.42 KDa
-
UniProt
- P01127
抗原
-