Quick Overview for PDGF-BB Homodimer 蛋白 (ABIN7455626)
抗原
PDGF-BB Homodimer
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
Greater than 98 % as determined by reducing SDS-PAGE.
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原理
- Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Affinity purification
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PDGF-BB Homodimer (Active) protein (His tag)
宿主: 人 宿主: 酵母菌 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
PDGF-BB Homodimer (AA 82-190) (Active) protein宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing (R) and non-reducing (NR) SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- PDGF-BB Homodimer
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别名
- PDGF-BB
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背景
- Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
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分子量
- 12.42 KDa
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UniProt
- P01127
抗原
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