Quick Overview for CCL1 蛋白 (ABIN7455623)
抗原
See all CCL1 蛋白
CCL1
(Chemokine (C-C Motif) Ligand 1 (CCL1))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
纯度
Greater than 95 % as determined by reducing SDS-PAGE.
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原理
- Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Affinity purification
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Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) protein (His tag)
CCL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 1-96) protein (GST tag)CCL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
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别名
- CCL1
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背景
- Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42 % amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
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分子量
- 8.62 KDa
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UniProt
- P22362
抗原
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