产品编号 ABIN7455618
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for IL-37 蛋白 (ABIN7455618)
抗原
See all IL-37 (IL37) 蛋白
IL-37 (IL37)
(Interleukin 37 (IL37))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)
纯度
Greater than 95 % as determined by reducing SDS-PAGE.
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原理
- Recombinant Human Interleukin-37 is produced by our E.coli expression system and the target gene encoding Lys53-Asp218 is expressed.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Affinity purification
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Interleukin 37 (IL37) (AA 1-218) protein (GST tag)
IL37 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 37 (IL37) (Active) proteinIL37 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM DTT, pH 7.4.
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- IL-37 (IL37) (Interleukin 37 (IL37))
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别名
- IL-37
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背景
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Interleukin-37,FIL1 Zeta,IL-1X,Interleukin-1 Family Member 7,IL-1F7,Interleukin-1 Homolog 4,IL-1H,IL-1H4,Interleukin-1 Zeta,IL-1 Zeta,Interleukin-1-Related Protein,IL-1RP1,Interleukin-23,IL-37,IL37,FIL1Z,IL1F7,IL1H4,IL1RP1
Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 Ra with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18. -
分子量
- 18.7 KDa
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UniProt
- Q9NZH6
抗原
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