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IL-37 蛋白

This Recombinant IL-37 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7455618
发货至: 中国

Quick Overview for IL-37 蛋白 (ABIN7455618)

抗原

See all IL-37 (IL37) 蛋白
IL-37 (IL37) (Interleukin 37 (IL37))

蛋白类型

Recombinant

宿主

资源

  • 9
  • 4
  • 1
大肠杆菌(E. Coli)

纯度

Greater than 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Interleukin-37 is produced by our E.coli expression system and the target gene encoding Lys53-Asp218 is expressed.

    产品特性

    Extracellular Domain Protein

    纯化方法

    Affinity purification
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM DTT, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    IL-37 (IL37) (Interleukin 37 (IL37))

    别名

    IL-37

    背景

    Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 Ra with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.

    分子量

    18.7 KDa

    UniProt

    Q9NZH6
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