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Neuropilin 1 Protein (NRP1) (AA 22-856) (His tag)

This Recombinant Neuropilin 1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7491103
发货至: 中国

Quick Overview for Neuropilin 1 Protein (NRP1) (AA 22-856) (His tag) (ABIN7491103)

抗原

See all Neuropilin 1 (NRP1) 蛋白
Neuropilin 1 (NRP1)

蛋白类型

Recombinant

宿主

  • 20
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  • 1

资源

  • 13
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HEK-293 Cells

纯度

The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 22-856

    标记

    This Neuropilin 1 protein is labelled with His tag.

    原理

    Recombinant human NRP1 protein with C-terminal 6xHis tag

    特异性

    NRP1 (Phe22-Pro856) 6xHis tag

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Neuropilin 1 (NRP1)

    别名

    CD304

    背景

    This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Nov 2020]

    分子量

    predicted molecular mass of 94.6 kDa after removal of the signal peptide. The apparent molecular mass of CD304-His is 100-130 kDa due to glycosylation.

    UniProt

    O14786

    途径

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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