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ITGA2 Protein (AA 30-1132) (His tag)

This Recombinant ITGA2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7490739
发货至: 中国

Quick Overview for ITGA2 Protein (AA 30-1132) (His tag) (ABIN7490739)

抗原

See all ITGA2 蛋白
ITGA2 (Integrin alpha 2 (ITGA2))

蛋白类型

Recombinant

宿主

  • 4
  • 2
  • 1
  • 1

资源

  • 7
  • 1
HEK-293 Cells

纯度

The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 30-1132

    标记

    This ITGA2 protein is labelled with His tag.

    原理

    Recombinant human ITGA2 Protein with C-terminal 6xHis tag

    特异性

    ITGA2 (Thr30-Thr1132) 6xHis tag

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    ITGA2

    背景

    This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

    分子量

    predicted molecular mass of 121.8 kDa after removal of the signal peptide. The apparent molecular mass of ITGA2-His is 130-250 kDa due to glycosylation.

    UniProt

    P17301

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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