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Claudin 6 Protein-VLP (CLDN6) (AA 1-219)

Name: Claudin 6 Protein-VLP (CLDN6) (AA 1-219)
Brand: antibodies-online
SKU: ABIN7448164
Availability: OutOfStock

This VLP Claudin 6 protein is expressed in HEK-293 Cells.

Immobilized Mouse Claudin 6 VLP at 5 μg/mL (100 μL/Well) on the plate. (Claudin 6 Protein-VLP (CLDN6) (AA 1-219))

ELISA

SEC-HPLC

2 images

产品编号 ABIN7448164

发货至: 中国

Datasheet as PDF

Quick Overview for Claudin 6 Protein-VLP (CLDN6) (AA 1-219) (ABIN7448164)

抗原

See all Claudin 6 (CLDN6) 蛋白

Claudin 6 (CLDN6)

蛋白类型

VLP

生物活性

Active

宿主

小鼠

资源

HEK-293 Cells

应用范围

ELISA, Immunogen (Imm), Surface Plasmon Resonance (SPR), Functional Studies (Func)

纯度

> 95 % as determined by HPLC

Discover our top product CLDN6 蛋白

产品特性

AA 1-219

原理

Mouse Claudin 6 Protein-VLP

序列

Met1-Val219

产品特性

Recombinant Mouse Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val219.

过滤

0.22 μm filtered

内毒素水平

Less than 1EU per μg by the LAL method.

Biological Activity Comment

Immobilized Mouse Claudin 6 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.6ng/ml determined by ELISA.
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Product

表达系统

Conjugate

Origin

价格从

Claudin 6 Protein (CLDN6) (AA 1-219) (His tag)

表达系统 HEK-293 Cells

Conjugate His tag

Origin Mouse

价格从 115,504.49 ¥

Claudin 6 Protein (CLDN6) (AA 1-219) (Strep Tag)

表达系统 Cell-free protein synthesis (CFPS)

Conjugate Strep Tag

Origin Mouse

价格从 152,621.24 ¥

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Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 宿主: 人宿主: HEK-293 Cells VLP > 95 % as determined by HPLC. ELISA, Imm, SPR, Func Active

Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 宿主: Cynomolgus 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active

Claudin 6 (CLDN6) (AA 1-220) protein (His tag)
custom-made CLDN6 宿主: 人宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Claudin 6 (CLDN6) (AA 1-219) protein (His tag)
custom-made CLDN6 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Claudin 6 (CLDN6) protein
CLDN6 宿主: 人宿主: Mammalian Cells MNP Membrane Nanoparticle

Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP (Biotin)
CLDN6 宿主: 人宿主: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Imm, SPR, Func Active

Claudin 6 (CLDN6) protein
CLDN6 宿主: 人宿主: HEK-293 Cells Synthetic Nanodisc

Claudin 6 (CLDN6) (AA 138-160) protein (mFc Tag)
CLDN6 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Claudin 6 (CLDN6) (AA 1-220) protein (GST tag)
CLDN6 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

Claudin 6 (CLDN6) (AA 138-160) protein (Fc Tag)
CLDN6 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

应用备注
- Antibody Discovery: Immunization, Screening, Functional Characterization
- Affinity determination: ELISA, SPR
- In vivo pharmacokinetic analysis
- CMC method development
- CAR-T Positive Rate Detection
- Blood sample determination: ELISA
说明

Virus-like particles (VLPs) are formed from the outer capsid protein of a virus and are tiny nanoparticles formed by the automatic assembly of one or more capsid proteins. VLPs do not contain viral infectious genomes, so they are relatively safe during production operations. The SAMS™ protein engineering platform has been used to express a series of biotinylated, non-biotinylated, and fluorescently-labeled VLP-displayed antigens. They are suitable for SPR, ELISA, CAR-T positive rate detection, and other experimental scenarios.

Virus-Like Particles (VLPs) are highly immunogenic, meaning that they can elicit a strong immune response in the host. VLPs are recognized by the immune system and are taken up by antigen-presenting cells (APCs) such as dendritic cells. Once taken up by APCs, VLPs are processed and presented to T cells, which can trigger the activation of B cells to produce antibodies against the displayed antigen. Because VLPs resemble the structure and composition of native viruses, they are highly effective at inducing both humoral and cellular immune responses.

Generally, VLPs range in size from approximately 20 to 200 nanometers (nm). Compared to a cell-based immunization approach, their smaller size can optimize the immune response to target the specific antigen displayed on the surface of the engineered VLPs.

限制

仅限研究用
状态

Liquid

缓冲液

Supplied as 0.22μm filtered solution in PBS, 300 mM L-Arginine ( pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.

储存条件

-80 °C

储存方法

Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

有效期

12 months
抗原

Claudin 6 (CLDN6)

别名

Claudin 6

背景

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88 % and 86 % amino acid sequence identity with mouse and rat Claudin-6, respectively.

分子量

24.60 kDa.

UniProt

Q9Z262

途径

Hepatitis C