Tspan-8 Protein (His tag)
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- 抗原 See all Tspan-8 (TSPAN8) 蛋白
- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This Tspan-8 protein is labelled with His tag.
- 原理
- Cynomolgus TSPAN8 Protein, His Tag
- 序列
- Lys 110 - Ser 205
- 产品特性
- Cynomolgus TSPAN8, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 110 - Ser 205 (Accession # G7PI18-1).
- 纯度
- 90,00 %
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product TSPAN8 蛋白
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Tetraspanin 8 (TSPAN8) (AA 110-205) protein (Fc Tag)
TSPAN8 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (Strep Tag)Crystallography grade TSPAN8 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tetraspanin 8 (TSPAN8) (AA 1-235) protein (Strep Tag)Crystallography grade TSPAN8 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 说明
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This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 17-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
- 别名
- TSPAN8 (TSPAN8 产品)
- 别名
- tm4sf3 Protein, MGC64550 Protein, GB13255 Protein, TM4SF3 Protein, tetraspanin-8 Protein, tspan8 Protein, TSPAN8 Protein, CO-029 Protein, C76990 Protein, E330007O21Rik Protein, Tm4sf3 Protein, CO-29 Protein, TSPAN-8 Protein, tetraspanin 8 L homeolog Protein, tetraspanin-1 Protein, tetraspanin 8 Protein, tspan8.L Protein, LOC409511 Protein, TSPAN8 Protein, tspan8 Protein, Tspan8 Protein
- 背景
- Synonyms:CO-029,tetraspanin 8,TM4SF3,TM4SF3tspan-8,Transmembrane 4 superfamily member 3tetraspanin-8,TSPAN8,Tspan-8,Tumor-associated antigen CO-029,Description:Tspan8 is 1 of the 33 mammalian members of the tetraspanin family, composed of transmembrane proteins that organize laterally, together or with other membrane partners such as integrins, to form 'tetraspanin webs'. These platforms signal within cells to regulate many cellular processes: adhesion, migration, invasion or survival Tspan8 has been implicated in many types of cancer.Overexpression was reported in glioma and colorectal, esophageal, hepatic, gastric and pancreatic carcinoma. Tspan8 exerts a pro-invasive function by controlling cell-cell and cell-matrix interactions through its association with membrane partners such as α6β4 integrin-protein kinase C (PKC)-activated, E-cadherin, EpCAM, claudin-7 and CD44. Moreover, Tspan8 may be a promising new therapeutic target, as Tspan8-specific antibodies were shown to reduce cell motility, block tumor angiogenesis in vivo.
- 分子量
- 12.7 kDa
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