IgG1 Protein (C103S, H316K, M135Y, N317F, S137T, T139E) (His tag)
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Quick Overview for IgG1 Protein (C103S, H316K, M135Y, N317F, S137T, T139E) (His tag) (ABIN7447926)
抗原
See all IgG1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- C103S, H316K, M135Y, N317F, S137T, T139E
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标记
- This IgG1 protein is labelled with His tag.
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原理
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag
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序列
- Glu 99 - Lys 330
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产品特性
- Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.1 kDa. The protein migrates as 30-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
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储存条件
- -20 °C
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储存方法
- -20°C
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- IgG1
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物质类
- Antibody
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背景
- Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
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分子量
- 28.1 kDa
抗原
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