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TGFB3 Protein (AA 301-412)

This Recombinant TGFB3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7275712
发货至: 中国

Quick Overview for TGFB3 Protein (AA 301-412) (ABIN7275712)

抗原

See all TGFB3 蛋白
TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE
  • 产品特性

    AA 301-412

    原理

    Human Mature TGF beta 3 Protein

    序列

    Ala301-Ser412

    产品特性

    Recombinant Human Mature TGF beta 3 Protein is expressed from HEK293 without tag.It contains Ala301-Ser412.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human Mature TGF beta 3, No Tag at 1μg (100μl/Well) on the plate. Dose response curve for Human TGF-beta RII, hFc Tag with the EC50 of 15.3ng/ml determined by ELISA. See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCl.

    缓冲液

    Lyophilized from 0.22μm filtered solution in 4 mM HCl. Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

    别名

    TGF beta 3

    背景

    Transforming growth factor-beta 3 is a cytokine which is involved in cell growth regulation and differentiation, stimulation of extracellular matrix and modulation of immune responses. TGF beta 3 RNA is expressed in a diverse array of tissues including perichondrium, bone, intervertebral discs, mesenteries, pleura, heart, lung, palate, and amnion, as well as in central nervous system (CNS) structures such as the meninges, choroid plexus and the olfactory bulbs. Furthermore, in several organ systems, TGF beta 3 transcripts are expressed during periods of active morphogenesis suggesting that the protein may be an important factor for the growth and differentiation of many embryonic tissues.

    分子量

    12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

    UniProt

    P10600-1

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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