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IL1RL2 Protein (AA 20-335) (His-Avi Tag)

This Recombinant IL1RL2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7274902
发货至: 中国

Quick Overview for IL1RL2 Protein (AA 20-335) (His-Avi Tag) (ABIN7274902)

抗原

See all IL1RL2 蛋白
IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

蛋白类型

Recombinant

宿主

  • 12
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资源

  • 6
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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 20-335

    标记

    This IL1RL2 protein is labelled with His-Avi Tag.

    原理

    Human IL-1 Rrp2/IL-1 R6 Protein

    序列

    Asp20-Arg335

    产品特性

    Recombinant Human IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp20-Arg335.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-1 Rrp2, His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-IL-1Rrp2 Antibody, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA. See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

    别名

    IL-1 Rrp2

    背景

    The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL-1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL-1 (TIGIRR-2/IL-1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

    分子量

    39.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

    UniProt

    Q9HB29-1
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