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IgE Protein (AA 198-421) (His-Avi Tag)

This Recombinant IgE protein is expressed in HEK-293 Cells.
产品编号 ABIN7274857
发货至: 中国

Quick Overview for IgE Protein (AA 198-421) (His-Avi Tag) (ABIN7274857)

抗原

See all IgE 蛋白
IgE

蛋白类型

Recombinant

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资源

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 198-421

    标记

    This IgE protein is labelled with His-Avi Tag.

    原理

    Mouse IgE Protein

    序列

    Asp198-Ser421

    产品特性

    Recombinant Mouse IgE Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp198-Ser421.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IgE

    背景

    Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

    分子量

    28.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.

    UniProt

    P06336
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