GDF15 Protein (AA 197-308) (Fc Tag,Biotin)
Quick Overview for GDF15 Protein (AA 197-308) (Fc Tag,Biotin) (ABIN7274726)
抗原
See all GDF15 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 197-308
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标记
- This GDF15 protein is labelled with Fc Tag,Biotin.
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原理
- Biotinylated Human GDF15 Protein (Primary Amine Labeling)
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序列
- Ala197-Ile308
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产品特性
- Recombinant Biotinylated Human GDF15 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala197-Ile308.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human GFRAL, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human GDF15, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA. See testing image for detail.
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Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (His tag)
GDF15 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag)GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag,Biotin)GDF15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 193-308) protein (His tag)GDF15 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (His tag)GDF15 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 197-308) protein (Fc Tag)GDF15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 197-307) protein (His tag)GDF15 宿主: 犬 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (Fc Tag,Biotin)GDF15 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Differentiation Factor 15 (GDF15) (AA 189-303) protein (His tag)GDF15 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
- GDF15
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背景
- Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
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分子量
- 37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
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UniProt
- Q99988
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途径
- SARS-CoV-2 Protein Interactome
抗原
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