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Desmoglein 3 Protein (DSG3) (AA 50-617) (His tag)

This Recombinant Desmoglein 3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7274503
发货至: 中国
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Quick Overview for Desmoglein 3 Protein (DSG3) (AA 50-617) (His tag) (ABIN7274503)

抗原

See all Desmoglein 3 (DSG3) 蛋白
Desmoglein 3 (DSG3)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 13
  • 1
小鼠

资源

  • 4
  • 4
  • 2
  • 1
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  • 1
HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC
  • 产品特性

    AA 50-617

    标记

    This Desmoglein 3 protein is labelled with His tag.

    原理

    Mouse DSG3 Protein

    序列

    Glu50-Pro617

    产品特性

    Recombinant Mouse DSG3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu50-Pro617.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Mouse DSG3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse DSG3 is greater than 90% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Desmoglein 3 (DSG3)

    别名

    DSG3

    背景

    To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.

    分子量

    64.3 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.

    UniProt

    O35902
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