Desmoglein 3 Protein (DSG3) (AA 50-617) (His tag)
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Quick Overview for Desmoglein 3 Protein (DSG3) (AA 50-617) (His tag) (ABIN7274503)
抗原
See all Desmoglein 3 (DSG3) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 50-617
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标记
- This Desmoglein 3 protein is labelled with His tag.
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原理
- Mouse DSG3 Protein
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序列
- Glu50-Pro617
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产品特性
- Recombinant Mouse DSG3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu50-Pro617.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse DSG3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse DSG3 is greater than 90% as determined by SEC-HPLC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Desmoglein 3 (DSG3)
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别名
- DSG3
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背景
- To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.
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分子量
- 64.3 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.
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UniProt
- O35902
抗原
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