Desmoglein 2 Protein (DSG2) (AA 50-609) (His tag)
This Recombinant Desmoglein 2 protein is expressed in HEK-293 Cells.
Quick Overview for Desmoglein 2 Protein (DSG2) (AA 50-609) (His tag) (ABIN7274500)
抗原
See all Desmoglein 2 (DSG2) 蛋白
Desmoglein 2 (DSG2)
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 95 % as determined by Tris-Bis PAGE
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产品特性
- AA 50-609
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标记
- This Desmoglein 2 protein is labelled with His tag.
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原理
- Human DSG-2/Desmoglein-2 Protein
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序列
- Ala50-Gly609
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产品特性
- Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.
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Desmoglein 2 (DSG2) (AA 55-618) protein (His tag)
DSG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Desmoglein 2 (DSG2) (AA 24-609) protein (His tag)DSG2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Desmoglein 2 (DSG2)
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别名
- DSG-2
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背景
- Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
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分子量
- 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
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UniProt
- Q14126
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途径
- Cell-Cell Junction Organization
抗原
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