CADM1 Protein (AA 45-374) (His tag)
Quick Overview for CADM1 Protein (AA 45-374) (His tag) (ABIN7274016)
抗原
See all CADM1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 45-374
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标记
- This CADM1 protein is labelled with His tag.
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原理
- Human CADM1/IGSF4A Protein
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序列
- Gln45-His374
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产品特性
- Recombinant Human CADM1/IGSF4A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln45-His374.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human CADM1, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CADM1 Antibody, hFc Tag with the EC50 of 8.5g/ml determined by ELISA. See testing image for detail.
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Cell Adhesion Molecule 1 (CADM1) (AA 48-388) protein (His tag)
CADM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cell Adhesion Molecule 1 (CADM1) (Active) protein (Fc Tag)CADM1 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE Active
Cell Adhesion Molecule 1 (CADM1) (AA 1-377) protein (His tag)CADM1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cell Adhesion Molecule 1 (CADM1) (AA 45-374) protein (His tag)CADM1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85% by SDS-PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- CADM1 (Cell Adhesion Molecule 1 (CADM1))
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别名
- CADM1
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背景
- The cell adhesion molecule 1 (CADM1) is a molecule of cell adhesion with multiple functions and has been identified as a tumor suppressor gene. CADM1 has multifunctions on the pathogenesis of malignancies, and other normal cells such as immune cells. On the contrary to these cutaneous solid tumors except for Merkel cell carcinoma, cutaneous lymphomas, such as adult-T cell leukemia/lymphoma, mycosis fungoides, and Sézary syndrome, increase their CADM1 expression for the development of tumor environment.
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分子量
- 38 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q9BY67-1
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
抗原
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