BACE1 Protein (AA 22-457) (His tag)
Quick Overview for BACE1 Protein (AA 22-457) (His tag) (ABIN7273904)
抗原
See all BACE1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 22-457
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标记
- This BACE1 protein is labelled with His tag.
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原理
- Human BACE-1 Protein
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序列
- Thr22-Thr457
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产品特性
- Recombinant Human BACE-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr22-Thr457.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Beta-secretase 1 (BACE1) (AA 22-457) protein (Fc Tag)
BACE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Beta-secretase 1 (BACE1) (AA 22-457) protein (His tag)BACE1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Beta-secretase 1 (BACE1) (AA 46-152) protein (His-IF2DI Tag)BACE1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Beta-secretase 1 (BACE1) (AA 22-501) protein (GST tag)BACE1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Beta-secretase 1 (BACE1) (Active) protein (His tag)BACE1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Beta-secretase 1 (BACE1) (AA 22-457) proteinBACE1 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- BACE-1
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背景
- The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.
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分子量
- 49.5 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
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NCBI登录号
- NP_036236
抗原
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