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APOA1 Protein (AA 25-267) (Fc Tag)

This Recombinant APOA1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7273867
发货至: 中国

Quick Overview for APOA1 Protein (AA 25-267) (Fc Tag) (ABIN7273867)

抗原

See all APOA1 蛋白
APOA1 (Apolipoprotein A-I (APOA1))

蛋白类型

Recombinant

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 25-267

    标记

    This APOA1 protein is labelled with Fc Tag.

    原理

    Human APOA1 Protein

    序列

    Asp25-Gln267

    产品特性

    Recombinant Human APOA1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp25-Gln267.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    APOA1

    背景

    Apolipoprotein A1 (ApoA1) is a main protein moiety in high-density lipoprotein (HDL) particles. Generally, ApoA1 and HDL are considered as atheroprotective. In prooxidant and inflammatory microenvironment in the vicinity to the atherosclerotic lesion, ApoA1/HDL are subjected to modification. The chemical modifications such as oxidation, nitration, etc result in altering native architecture of ApoA1 toward dysfunctionality and abnormality.

    分子量

    54.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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