ApoE3 Protein (AA 19-317) (His tag)
ApoE3
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 抗原 See all ApoE3 products
- ApoE3 (Apolipoprotein E3 (ApoE3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-317
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ApoE3 protein is labelled with His tag.
- 原理
- Human APOE3/Apolipoprotein E Protein
- 序列
- Lys19-His317
- 产品特性
- Recombinant Human APOE3/Apolipoprotein E Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Lys19-His317.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.004 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Apolipoprotein E3 (ApoE3) (AA 19-317) protein (His tag,Biotin)
ApoE3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ApoE3 (Apolipoprotein E3 (ApoE3))
- 别名
- APOE3 (ApoE3 产品)
- 别名
- AD2 Protein, LDLCQ5 Protein, LPG Protein, apolipoprotein E Protein, APOE Protein
- 背景
- Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
- 分子量
- 35.3 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
- 途径
- Regulation of Cell Size, Lipid Metabolism
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