BTN3A1 Protein (Biotin)
Quick Overview for BTN3A1 Protein (Biotin) (ABIN7319892)
抗原
See all BTN3A1 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This BTN3A1 protein is labelled with Biotin.
-
原理
- Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated
-
序列
- Gln30-Gly254
-
产品特性
- Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
-
-
说明
-
58-62 kDa
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
-
别名
- BTN3A1
-
背景
-
Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5
-
分子量
- 52.6 kDa
-
UniProt
- O00481
-
途径
- Activated T Cell Proliferation
抗原
-