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BTN3A1 Protein (Biotin)

This Recombinant BTN3A1 protein is expressed in 人细胞.
产品编号 ABIN7319892
发货至: 中国

Quick Overview for BTN3A1 Protein (Biotin) (ABIN7319892)

抗原

See all BTN3A1 蛋白
BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

蛋白类型

Recombinant

宿主

  • 15
  • 3

资源

  • 12
  • 3
  • 2
  • 1
人细胞

纯度

>90 % as determined by reducing SDS-PAGE.
  • 标记

    This BTN3A1 protein is labelled with Biotin.

    原理

    Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated

    序列

    Gln30-Gly254

    产品特性

    Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 说明

    58-62 kDa

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

    别名

    BTN3A1

    背景

    Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

    Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5

    分子量

    52.6 kDa

    UniProt

    O00481

    途径

    Activated T Cell Proliferation
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