Quick Overview for BTN2A2 Protein (Biotin) (ABIN7319888)
抗原
See all BTN2A2 蛋白蛋白类型
宿主
资源
纯度
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标记
- This BTN2A2 protein is labelled with Biotin.
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原理
- Recombinant Human Butyrophilin Subfamily 2 Member A2/BTN2A2 (C-Fc-Avi) Biotinylated
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序列
- Gln33-Val237
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产品特性
- Biotinylated Recombinant Human Butyrophilin Subfamily 2 Member A2 is produced by our Mammalian expression system and the target gene encoding Gln33-Val237 is expressed with a Fc, Avi tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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butyrophilin, Subfamily 2, Member A2 (BTN2A2) (AA 30-244) protein (His tag)
BTN2A2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
butyrophilin, Subfamily 2, Member A2 (BTN2A2) (AA 33-262), (Isoform 2), (partial) protein (His-SUMO Tag)BTN2A2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
butyrophilin, Subfamily 2, Member A2 (BTN2A2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BTN2A2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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说明
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55-80 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- BTN2A2 (butyrophilin, Subfamily 2, Member A2 (BTN2A2))
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别名
- BTN2A2
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背景
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Background: Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses. Mature human Butyrophilin 2A2 consisits of a 233 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 237 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A2 that lack the first, second, or both Iglike domains as well as isoforms with substitutions and deletions in the cytoplasmic region. Within the immune system, Butyrophilin 2A2 is expressed on thymic epithelial cells, naive B cells, splenic NK cells, dendritic cells, and peritoneal macrophages and is up-regulated with cell activation. Butyrophilin 2A2 inhibits T cell proliferation and activation and enhances the development of FoxP3+ regulatory T cells. Its up-regulation in the hippocampus is associated with schizophrenia.
Synonym: Butyrophilin subfamily 2 member A2, BTN2A2
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分子量
- 51.5 kDa
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UniProt
- Q8WVV5
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途径
- Activated T Cell Proliferation
抗原
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