APOA1 Protein (AA 19-267)
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北京 101111
Quick Overview for APOA1 Protein (AA 19-267) (ABIN7318169)
抗原
See all APOA1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-267
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原理
- Recombinant Human Apolipoprotein A-I/ApoAI Protein
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序列
- Arg19-Gln267
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产品特性
- Recombinant Human Apolipoprotein A-I is produced by our E.coli expression system and the target gene encoding Arg19-Gln267 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Apolipoprotein A-I (APOA1) (AA 25-267) (Active) protein (hFc Tag)
APOA1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Apolipoprotein A-I (APOA1) (AA 25-264) (Active) protein (hFc Tag)APOA1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Apolipoprotein A-I (APOA1) (AA 1-267) protein (GST tag)APOA1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Apolipoprotein A-I (APOA1) (AA 25-267) protein (His tag)APOA1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apolipoprotein A-I
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背景
- APOA1,Apo-AI,ApoA-I,Apolipoprotein A-I,Apolipoprotein A1,Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
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分子量
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Calculated MW: 29.0 kDa
Observed MW: 25-31 kDa
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基因ID
- 335
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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