APOA1 Protein (His tag)
Quick Overview for APOA1 Protein (His tag) (ABIN7198959)
抗原
See all APOA1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This APOA1 protein is labelled with His tag.
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原理
- Recombinant Human Apolipoprotein A-I/ApoAI Protein (His Tag)
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序列
- Asp25-Gln267
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产品特性
- A DNA sequence encoding the mature form of human APOA1 (P02647) (Asp25-Gln267) was expressed with a polyhistidine tag at the N-terminus.
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内毒素水平
- Please contact us for more information.
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说明
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27-31 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, 10 % Glycerol, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apolipoprotein A-I
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背景
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Background: Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
Synonym: Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, APOA1
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分子量
- 30.7 kDa
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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