Tryptophan Synthetase protein (His tag)
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北京 101111
Quick Overview for Tryptophan Synthetase protein (His tag) (ABIN7320985)
抗原
蛋白类型
宿主
资源
纯度
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标记
- His tag
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原理
- Recombinant E.coli Tryptophan Synthase Protein (His Tag)
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序列
- Met1-Ser268&Thr2-Ile397
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产品特性
- Recombinant E.coli Tryptophan synthase is produced by our E.coli expression system and the target gene encoding Met1-Ser268&Thr2-Ile397 is expressed with a 6His tag at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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说明
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28&40-50 kDa
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Tryptophan Synthetase
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别名
- Tryptophan Synthase
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背景
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Background: Tryptophan synthase is a multienzyme α2β2 complex composed of two protein subunit. Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp). The α-subunit catalyzes cleavage of 3-indole-d-glycerol 3'-phosphate (IGP) to give indole and D-glyceraldehyde 3'-phosphate (G3P). Indole is then transferred through a 25-? hydrophobic tunnel to the β-subunit. The β2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.
Synonym: Tryptophan synthetase, Tryptophan synthase
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分子量
- 72.5 kDa
抗原
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