Quick Overview for CD24 Protein (Biotin) (ABIN7319889)
抗原
See all CD24 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CD24 protein is labelled with Biotin.
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原理
- Recombinant Human Signal Transducer CD24/CD24 (C-Fc-Avi) Biotinylated
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序列
- Ser27-Gly59
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产品特性
- Biotinylated Recombinant Human Signal Transducer CD24 is produced by our Mammalian expression system and the target gene encoding Ser27-Gly59 is expressed with a Fc, Avi tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Immobilized Anti-Human CD24 mAb(Cat#NC050) at 2μg/ml (100 μl/well) can bind Biotinylated Human CD24-Fc-Avi(Cat#CY43). The ED50 of Biotinylated Human CD24-Fc-Avi(Cat#CY43) is 1.83 ng/ml.
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CD24 Molecule (CD24) (AA 27-59) protein (Llama Fc Tag)
CD24 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 94 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-59) protein (mFc Tag)CD24 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-59) protein (Fc Tag)CD24 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-59) protein (Fc Tag,Biotin)CD24 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (Active) protein (mFc Tag)CD24 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
CD24 Molecule (CD24) (Active) protein (Fc Tag)CD24 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
CD24 Molecule (CD24) (AA 27-53) protein (mFc Tag)CD24 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-54) protein (Fc Tag)CD24 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-59) protein (mFc Tag,Biotin)CD24 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD24 Molecule (CD24) (AA 27-54) protein (Fc Tag,Biotin)CD24 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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说明
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40-55 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD24 (CD24 Molecule (CD24))
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别名
- CD24
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背景
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Background: Signal Transducer CD24 is a heavily and variably glycosylated GPI-linked sialoprotein. Human CD24 is expressed on B lineage cells and granulocytes, on epithelial, neuronal, and muscle cells, and on a range of tumor cells. CD24 expression is regulated during lineage development and with the activation of various cell types. Antibody crosslinking of CD24 enhances the induction of apoptosis in B and T lymphocytes which contributes to negative selection and the induction of immune tolerance. CD24 on antigen presenting cells cooperates with B7 Molecules in the costimulation of T cells. CD24 associates in cis with Siglec10 and with the danger-associated molecules HMGB1, HSP70, or HSP90 which are released from necrotic or damaged cells. Formation of these ternary complexes fills a protective role: the resulting Siglec10 signaling inhibits inflammatory responses that are otherwise induced by extracellular DAMPs.
Synonym: Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, CD24, CD24A
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分子量
- 31.6 kDa
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UniProt
- P25063
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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