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TNNC1 蛋白

This Recombinant TNNC1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7317698
发货至: 中国
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Quick Overview for TNNC1 蛋白 (ABIN7317698)

抗原

See all TNNC1 蛋白
TNNC1 (Cardiac Troponin C (TNNC1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Troponin C/TNNC1 Protein

    序列

    Met 1-Glu161

    产品特性

    A DNA sequence encoding the human TNNC1 (NP_003271.1) (Met1-Glu161) was expressed and purified.

    内毒素水平

    Please contact us for more information.
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    表达系统
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    表达系统 HEK-293 Cells
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  • 说明

    20 kDa

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile 150 mM NaCl, 10 mM Na2HPO4, pH 7.5

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    TNNC1 (Cardiac Troponin C (TNNC1))

    别名

    TNNC1

    背景

    Background: Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

    Synonym: CMD1Z,CMH13,TN-C,TNC,TNNC

    分子量

    18.4 kDa

    NCBI登录号

    NP_003271
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