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UBE2H 蛋白

This Recombinant UBE2H protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7198586
发货至: 中国
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Quick Overview for UBE2H 蛋白 (ABIN7198586)

抗原

See all UBE2H 蛋白
UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

蛋白类型

Recombinant

宿主

  • 10
  • 1

资源

  • 5
  • 3
  • 1
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

> 93 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human Ube2H Protein

    序列

    Met 1-Leu 183

    产品特性

    A DNA sequence encoding the human UBE2H (P62256) (Met 1-Leu 183) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 127,054.94 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, 10 % glycerol, 2 mM DTT, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    UBE2H (Ubiquitin-Conjugating Enzyme E2H (UBE2H))

    别名

    Ube2H

    背景

    Background: UBE2H is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation; ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction; and thereby the fate of the substrate; is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space; a highly sophisticated conjugation machinery has been developed. In a sequential manner; ubiquitin becomes activated by an ubiquitin-activating enzyme (E1); which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next; ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system; wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. 

    Synonym: Ubiquitin-Conjugating Enzyme E2 H; UbcH2; Ubiquitin Carrier Protein H; Ubiquitin-Conjugating Enzyme E2-20K; Ubiquitin-Protein Ligase H; UBE2H;E2-20K;GID3;UBC8;UBCH;UBCH2

    UniProt

    P62256
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