TACSTD2 Protein (His tag,Fc Tag)
Our Local Distributor
北京 101111
Quick Overview for TACSTD2 Protein (His tag,Fc Tag) (ABIN7198531)
抗原
See all TACSTD2 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
标记
- This TACSTD2 protein is labelled with His tag,Fc Tag.
-
原理
- Recombinant Human TROP2/TACSTD2 Protein (His & Fc Tag)(Active)
-
序列
- Met 1-Thr 274
-
产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Thr 274) of human TROP2 (NP_002344.2) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When cells are added to coated plates (10μg/ml,100μl/well), approximately 55%-70% will adhere specifically.
-
-
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) (Active) protein (His tag)
TACSTD2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) (Active) protein (Biotin,His-Avi Tag)TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (His tag)TACSTD2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (Fc Tag)TACSTD2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (His tag,Biotin)TACSTD2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (Active) protein (His tag)TACSTD2 宿主: 猕猴 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-274) protein (His tag,mFc Tag)TACSTD2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 25-270) protein (Fc Tag)TACSTD2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 25-270) (Active) protein (His tag)TACSTD2 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) (AA 27-323) protein (GST tag)TACSTD2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from sterile PBS, pH 7.4
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
-
别名
- TROP2/TACSTD2
-
背景
-
Background: TROP-2, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
Synonym: EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TACD2,TROP-2,TROP2
-
分子量
- 55.7 kDa
-
NCBI登录号
- NP_002344
抗原
-
