TPBG Protein (mFc Tag)
Quick Overview for TPBG Protein (mFc Tag) (ABIN7319827)
抗原
See all TPBG 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This TPBG protein is labelled with mFc Tag.
-
原理
- Recombinant Human TPBG/5T4 (C-mFc)
-
序列
- Ser32-Ser355
-
产品特性
- Recombinant Human Trophoblast glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a mFc tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- TPBG (Trophoblast Glycoprotein (TPBG))
-
别名
- TPBG/5T4
-
背景
-
Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Synonym: 5T4 , 5T4AG, M6P1, WAIF1
-
分子量
- 61.7 kDa
-
UniProt
- Q13641
抗原
-