TTR Protein (AA 21-147) (His tag)
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北京 101111
Quick Overview for TTR Protein (AA 21-147) (His tag) (ABIN7319108)
抗原
See all TTR 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 21-147
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标记
- This TTR protein is labelled with His tag.
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原理
- Recombinant Human Transthyretin/TTR Protein (His Tag)
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序列
- Gly21-Glu147
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产品特性
- Recombinant Human Transthyretin is produced by our Mammalian expression system and the target gene encoding Gly21-Glu147 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Transthyretin (TTR) (AA 21-147) (Active) protein (His tag)
TTR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Transthyretin (TTR) (AA 21-147) protein (GST tag)TTR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Transthyretin (TTR) (AA 23-147) protein (His tag)TTR 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Transthyretin (TTR) (AA 21-147) proteinTTR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- TTR (Transthyretin (TTR))
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别名
- Transthyretin/TTR
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背景
- ATTR,CTS,CTS1,HEL111,PALB,Prealbumin,TBPA,TTR,Transthyretin,Transthyretin is a secreted and cytoplasm protein which belongs to the Transthyretin family. Transthyretin is detected in serum and cerebrospinal fluid (at protein level). It is highly expressed in choroid plexus epithelial cells. It is also detected in retina pigment epithelium and liver. Each monomer of Transthyretin has two 4-stranded beta sheets and the shape of a prolate ellipsoid. Antiparallel beta-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex beta-sheets of the dimers to form an internal channel. Defects in Transthyretin are the cause of amyloidosis type 1 (AMYL1) which is a hereditary generalized amyloidosis due to transthyretin amyloid deposition. Protein fibrils can form in different tissues leading to amyloid polyneuropathies, amyloidotic cardiomyopathy, carpal tunnel syndrome, systemic senile amyloidosis. The disease includes leptomeningeal amyloidosis that is characterized by primary involvement of the central nervous system.
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分子量
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Calculated MW: 14.8 kDa
Observed MW: 17&36 kDa
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基因ID
- 7276
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UniProt
- P02766
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途径
- Hormone Transport
抗原
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