TLK1 Protein (His-GST)
This Recombinant TLK1 protein is expressed in Baculovirus infected Insect Cells.
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产品编号 ABIN7317054
发货至:
中国
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Quick Overview for TLK1 Protein (His-GST) (ABIN7317054)
抗原
See all TLK1 蛋白
TLK1
(Tousled-Like Kinase 1 (TLK1))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
Baculovirus infected Insect Cells
纯度
> 88 % as determined by reducing SDS-PAGE.
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标记
- This TLK1 protein is labelled with His-GST.
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原理
- Recombinant Human TLK1/PKU-beta Protein (His & GST Tag)
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序列
- Met 1-Tyr 766
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产品特性
- A DNA sequence encoding the human TLK1 isoform 1 (Q9UKI8-1) (Met 1-Tyr 766) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 1. 6 nmol/min/mg using Histone H3 protein as substrate.
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Tousled-Like Kinase 1 (TLK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)
TLK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- TLK1 (Tousled-Like Kinase 1 (TLK1))
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别名
- TLK1/PKU-beta
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背景
- KIAA0137,PKU-beta,The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
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Calculated MW: 114 kDa
Observed MW: 125 kDa
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基因ID
- 9874
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UniProt
- Q9UKI8
抗原
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