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Quick Overview for TIMP1 Protein (AA 25-205) (ABIN7320662)
抗原
See all TIMP1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 25-205
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原理
- Recombinant Mouse TIMP1/TIMP Protein
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序列
- Cys25-Arg205
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产品特性
- Recombinant Mouse Tissue Inhibitors of Metalloproteinases 1 is produced by our Mammalian expression system and the target gene encoding Cys25-Arg205 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-205) (Active) protein (hFc Tag)
TIMP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) protein (GST tag)TIMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) protein (Fc Tag)TIMP1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-217) (Active) proteinTIMP1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (Active) protein (His tag)TIMP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1/TIMP
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背景
- CLGI,Collagenase Inhibitor,EPA,Erythroid-Potentiating Activity,Fibroblast collagenase Inhibitor,Metalloproteinase Inhibitor 1,TIMP,TIMP-1,TIMP1,Tissue Inhibitor of Metalloproteinases 1,Mouse Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.
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分子量
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Calculated MW: 20.2 kDa
Observed MW: 26 kDa
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基因ID
- 21857
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UniProt
- P12032
抗原
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