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Thrombopoietin Protein (THPO) (His tag)

This Recombinant Thrombopoietin protein is expressed in 人细胞.
产品编号 ABIN7320657
发货至: 中国

Quick Overview for Thrombopoietin Protein (THPO) (His tag) (ABIN7320657)

抗原

See all Thrombopoietin (THPO) 蛋白
Thrombopoietin (THPO)

蛋白类型

Recombinant

宿主

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小鼠

资源

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人细胞

纯度

> 95 % as determined by SDS-PAGE
  • 标记

    This Thrombopoietin protein is labelled with His tag.

    原理

    Recombinant Mouse Thrombopoietin/TPO Protein (His Tag)

    序列

    Ser22-Thr356

    产品特性

    Recombinant Mouse Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22-Thr356 is expressed with a 6His tag at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Thrombopoietin (THPO)

    别名

    Thrombopoietin/TPO

    背景

    Background: Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets.Mature mouse Tpo shares 71 % and 81 % aa sequence homology with human and rat Tpo, respectively. It is an 80-85 kDa protein that consists of an N-terminal domain with homology to Erythropoietin (Epo) and a C-terminal domain that contains multiple N-linked and O-linked glycosylation sites. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

    Synonym: Thrombopoietin,C-mpl ligand,Megakaryocyte colony-stimulating factor,Megakaryocyte growth and development factor,Myeloproliferative leukemia virus oncogene ligand,THPO

    分子量

    36.4 kDa

    UniProt

    P40226

    途径

    JAK/STAT Signaling, Hormone Activity
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