Tspan-8 Protein (His tag)
-
- 抗原 See all Tspan-8 (TSPAN8) 蛋白
- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Tspan-8 protein is labelled with His tag.
- 原理
- Recombinant Human TSPAN8/Tetraspanin 8 Protein (His Tag)
- 序列
- Lys110-Asn205
- 产品特性
- A DNA sequence encoding the human TSPAN8 (P19075) (Lys110-Asn205) was expressed with an N-terminal polyhistidine tag.
- 纯度
- (87.8+10.7) % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product TSPAN8 蛋白
-
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (Fc Tag)
TSPAN8 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (Strep Tag)Crystallography grade TSPAN8 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Tetraspanin 8 (TSPAN8) (AA 1-235) protein (Strep Tag)Crystallography grade TSPAN8 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
- 别名
- TSPAN8/Tetraspanin 8 (TSPAN8 产品)
- 别名
- tm4sf3 Protein, MGC64550 Protein, GB13255 Protein, TM4SF3 Protein, tetraspanin-8 Protein, tspan8 Protein, TSPAN8 Protein, CO-029 Protein, C76990 Protein, E330007O21Rik Protein, Tm4sf3 Protein, CO-29 Protein, TSPAN-8 Protein, tetraspanin 8 L homeolog Protein, tetraspanin-1 Protein, tetraspanin 8 Protein, tspan8.L Protein, LOC409511 Protein, TSPAN8 Protein, tspan8 Protein, Tspan8 Protein
- 背景
-
Background: Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a negative regulator of Tspan8 expression. p53 as a regulator of melanoma invasion and the concept that reactivating p53 could provide a strategy for modulating not only proliferative but also invasive capacity in melanoma treatment. Tetraspanin 8 (TSPAN8) is a tumor-associated antigen implicated in tumor progression and metastasis. TSPAN8 may play an important role in mCRC cell invasion. TSPAN8 was overexpressed in human gastric cancer tissues and gastric cancer cell lines compared with the normal. TSPAN8 overexpression promoted cell proliferation and invasion, while TSPAN8 suppression inhibited cell proliferation and invasion. TSPAN8 could activate the ERK MAPK pathway in gastric cancer cells, and MEK-ERK inhibition reversed the effects of TSPAN8 overexpression on cell proliferation and invasion.
Synonym: CO-029,TM4SF3
- 分子量
- 13.4 kDa
- UniProt
- P19075
-
