Tspan-8 Protein (His tag)
Quick Overview for Tspan-8 Protein (His tag) (ABIN7198214)
抗原
See all Tspan-8 (TSPAN8) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Tspan-8 protein is labelled with His tag.
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原理
- Recombinant Human TSPAN8/Tetraspanin 8 Protein (His Tag)
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序列
- Lys110-Asn205
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产品特性
- A DNA sequence encoding the human TSPAN8 (P19075) (Lys110-Asn205) was expressed with an N-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 136,947.45 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Tetraspanin 8 (TSPAN8) (AA 1-237) protein (His tag)
custom-made TSPAN8 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 1-235) protein (His tag)custom-made TSPAN8 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (Fc Tag)TSPAN8 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tetraspanin 8 (TSPAN8) proteinTSPAN8 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
Tetraspanin 8 (TSPAN8) (AA 110-205) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) (AA 1-237) protein (GST tag)TSPAN8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tetraspanin 8 (TSPAN8) protein (Fc Tag)TSPAN8 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Tspan-8 (TSPAN8) (Tetraspanin 8 (TSPAN8))
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别名
- TSPAN8/Tetraspanin 8
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背景
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Background: Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a negative regulator of Tspan8 expression. p53 as a regulator of melanoma invasion and the concept that reactivating p53 could provide a strategy for modulating not only proliferative but also invasive capacity in melanoma treatment. Tetraspanin 8 (TSPAN8) is a tumor-associated antigen implicated in tumor progression and metastasis. TSPAN8 may play an important role in mCRC cell invasion. TSPAN8 was overexpressed in human gastric cancer tissues and gastric cancer cell lines compared with the normal. TSPAN8 overexpression promoted cell proliferation and invasion, while TSPAN8 suppression inhibited cell proliferation and invasion. TSPAN8 could activate the ERK MAPK pathway in gastric cancer cells, and MEK-ERK inhibition reversed the effects of TSPAN8 overexpression on cell proliferation and invasion.
Synonym: CO-029,TM4SF3
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分子量
- 13.4 kDa
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UniProt
- P19075
抗原
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