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TSPAN1 Protein (Fc Tag)

TSPAN1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317314
发货至: 中国
  • 抗原 See all TSPAN1 蛋白
    TSPAN1 (Tetraspanin 1 (TSPAN1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TSPAN1 protein is labelled with Fc Tag.
    原理
    Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag)
    序列
    Tyr110-Asn211
    产品特性
    A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TSPAN1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TSPAN1 (Tetraspanin 1 (TSPAN1))
    别名
    TSPAN1 (TSPAN1 产品)
    别名
    TSPAN1 Protein, 9030418M05Rik Protein, NET1 Protein, TM4C Protein, TM4SF Protein, tetraspanin 1 Protein, tetraspanin 1 L homeolog Protein, TSPAN1 Protein, tspan1.L Protein, Tspan1 Protein
    背景

    Background: TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone, in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.

    Synonym: NET1,TM4C,TM4SF,TSPAN1

    分子量
    39.1 kDa
    UniProt
    O60635
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