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TSPAN1 Protein (Fc Tag)

This Recombinant TSPAN1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7317314
发货至: 中国
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Quick Overview for TSPAN1 Protein (Fc Tag) (ABIN7317314)

抗原

See all TSPAN1 蛋白
TSPAN1 (Tetraspanin 1 (TSPAN1))

蛋白类型

Recombinant

宿主

  • 6
  • 2

资源

  • 2
  • 2
  • 2
  • 1
  • 1
HEK-293 Cells

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This TSPAN1 protein is labelled with Fc Tag.

    原理

    Recombinant Human TSPAN1 Protein (aa 110-211, Fc Tag)

    序列

    Tyr110-Asn211

    产品特性

    A DNA sequence encoding the human TSPAN1 (O60635)(Tyr110-Asn211) was expressed with the Fc region of rabbit IgG at the N-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 150,642.20 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 124,087.72 ¥
    145,985.55 ¥
    -15%

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    TSPAN1 (Tetraspanin 1 (TSPAN1))

    别名

    TSPAN1

    背景

    Background: TSPAN1 belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins have four hydrophobic domains, intracellular N- and C-termini and two extracellular domains. Tetraspanins act as scaffolding proteins, anchoring multiple proteins to one area of the cell membrane. They also mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN1 interacts with human thiamine transporter-1 (hTHTR-1). HTHTR-1 contributes to intestinal thiamine uptake, and its function is regulated at both the transcriptional and posttranscriptional levels. TSPAN1 and hTHTR-1 colocalize in human intestinal epithelial HuTu-80 cells. Coexpression of TSPAN1 in these cells led to a significant decrease in the rate of degradation of hTHTR-1 compared with cells expressing the hTHTR-1 alone, in fact the half-life of the TSPAN1 protein was twice longer in the former cell type compared with the latter cell type.

    Synonym: NET1,TM4C,TM4SF,TSPAN1

    分子量

    39.1 kDa

    UniProt

    O60635
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