TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST)
This Recombinant TAO Kinase 3 protein is expressed in Baculovirus infected Insect Cells.
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产品编号 ABIN7317073
发货至:
中国
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Quick Overview for TAO Kinase 3 Protein (TAOK3) (AA 1-411) (His-GST) (ABIN7317073)
抗原
See all TAO Kinase 3 (TAOK3) 蛋白
TAO Kinase 3 (TAOK3)
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
Baculovirus infected Insect Cells
纯度
> 92 % as determined by reducing SDS-PAGE.
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产品特性
- AA 1-411
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标记
- This TAO Kinase 3 protein is labelled with His-GST.
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原理
- Recombinant Human TAOK3/JIK/MAP3K18 Protein (aa 1-411, His & GST Tag)
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序列
- Met 1-Asp 411
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产品特性
- A DNA sequence encoding the amino acids (Met 1-Asp 411) of human TAOK3 (Q9H2K8-1) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.
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TAO Kinase 3 (TAOK3) (AA 1-898) protein (GST tag)
TAOK3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
TAO Kinase 3 (TAOK3) protein (Myc-DYKDDDDK Tag)TAOK3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 3 mM GSH, pH 7.4, 10 % glycerol
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- TAO Kinase 3 (TAOK3)
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别名
- TAOK3/JIK/MAP3K18
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背景
- DPK,JIK,MAP3K18,Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to theprotein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains oneprotein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.
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分子量
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Calculated MW: 74.3 kDa
Observed MW: 85 kDa
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基因ID
- 51347
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UniProt
- Q9H2K8
抗原
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