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STXBP3 Protein (His-GST)

This Recombinant STXBP3 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7317481
发货至: 中国
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Quick Overview for STXBP3 Protein (His-GST) (ABIN7317481)

抗原

See all STXBP3 蛋白
STXBP3 (Syntaxin Binding Protein 3 (STXBP3))

蛋白类型

Recombinant

宿主

  • 6
  • 2

资源

  • 3
  • 2
  • 2
  • 1
Baculovirus infected Insect Cells

纯度

> 82 % as determined by reducing SDS-PAGE.
  • 标记

    This STXBP3 protein is labelled with His-GST.

    原理

    Recombinant Human STXBP3/UNC-18C Protein (His & GST Tag)

    序列

    Met 1-Glu 592

    产品特性

    A DNA sequence encoding the human STXBP3 (O00186-1) (Met 1-Glu 592) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

    过滤

    0.2 μm filtered

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Not validated for activity
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
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    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5, 10 % glycerol
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    STXBP3 (Syntaxin Binding Protein 3 (STXBP3))

    别名

    STXBP3/UNC-18C

    背景

    MUNC18-3,MUNC18C,PSP,UNC-18C,Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to theSTXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STXBP3 participates in the consolidation and secretion of secondary and tertiary granules. STXBP3 contains one SEC1 domain. Phosphorylation at Ser129 may stimulate granule release. Human STXBP3 shares 90 % aa identity with mouse STXBP3. STXBP3 interacts with DOC2B, the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion. Interacts with STX4.

    分子量

    Calculated MW: 95.6 kDa

    Observed MW: 95.6 kDa

    基因ID

    6814

    UniProt

    O00186

    途径

    Hormone Transport
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