STXBP1 Protein (His-GST)
Our Local Distributor
北京 101111
Quick Overview for STXBP1 Protein (His-GST) (ABIN7317492)
抗原
See all STXBP1 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This STXBP1 protein is labelled with His-GST.
-
原理
- Recombinant Human STXBP1/UNC18A Protein (His & GST Tag)
-
序列
- Met 1-Ser 594
-
产品特性
- A DNA sequence encoding the human STXBP1 isoform 1 (P61764-1) (Met 1-Ser 594) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
-
Biological Activity Comment
- Not validated for activity
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Syntaxin Binding Protein 1 (STXBP1) (AA 1-594) protein (His tag)
custom-made STXBP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Syntaxin Binding Protein 1 (STXBP1) (AA 1-594) protein (His tag)custom-made STXBP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Syntaxin Binding Protein 1 (STXBP1) (AA 1-603) protein (GST tag)STXBP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Syntaxin Binding Protein 1 (STXBP1) (AA 74-168) protein (GST tag)STXBP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Syntaxin Binding Protein 1 (STXBP1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)STXBP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Syntaxin Binding Protein 1 (STXBP1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)STXBP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
-
Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 10 % glycerol, pH 8.0
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存液
- PMSF
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
有效期
- 12 months
-
-
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
-
别名
- STXBP1/UNC18A
-
背景
- MUNC18-1,NSEC1,P67,RBSEC1,UNC18,Syntaxin-binding protein 1, also known as N-Sec1, Protein unc-18 homolog 1, MUNC18-1 and STXBP1, is a peripheral membrane protein which belongs to theSTXBP / unc-18 / SEC1 family. STXBP1 is an evolutionally conserved neuronal Sec1/Munc-18 (SM) protein that is essential in synaptic vesicle release in several species. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. STXBP1 is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4. STXBP1 may also play a role in determining the specificity of intracellular fusion reactions. Defects in STXBP1 are the cause of epileptic encephalopathy early infantile type 4 (EIEE4). Affected individuals have neonatal or infantile onset of seizures, suppression-burst pattern on EEG, profound mental retardation, and MRI evidence of hypomyelination.
-
分子量
-
Calculated MW: 95.4 kDa
Observed MW: 80 kDa
-
基因ID
- 6812
-
UniProt
- P61764
-
途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
-
