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SNAP25 Protein (His tag)

This Recombinant SNAP25 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7317532
发货至: 中国

Quick Overview for SNAP25 Protein (His tag) (ABIN7317532)

抗原

See all SNAP25 蛋白
SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This SNAP25 protein is labelled with His tag.

    原理

    Recombinant Human SNAP25/SUP Protein (His Tag)

    序列

    Met 1-Gly 206

    产品特性

    A DNA sequence encoding the human SNAP25 (P60880-1) (Met 1-Gly 206) was expressed, with a polyhistide tag at the N-terminus.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

    别名

    SNAP25/SUP

    背景

    Background: Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein which belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP25 / SUP is a Q-SNARE protein contributing two α-helices in the formation of the exocytotic fusion complex in neurons where it assembles with syntaxin-1 and synaptobrevin. SNAP25 / SUP is involved in the molecular regulation of neurotransmitter release. It may play an important role in the synaptic function of specific neuronal systems. SNAP25 / SUP associates with proteins involved in vesicle docking and membrane fusion. SNAP25 / SUP regulates plasma membrane recycling through its interaction with CENPF. SNAP25 / SUP inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP25 / SUP decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.

    Synonym: bA416N4.2;dJ1068F16.2;RIC-4;RIC4;SEC9;SNAP;SNAP-25

    分子量

    24.8 kDa

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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