SPHK1 Protein (His-GST)
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北京 101111
Quick Overview for SPHK1 Protein (His-GST) (ABIN7317044)
抗原
See all SPHK1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This SPHK1 protein is labelled with His-GST.
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原理
- Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag)
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序列
- Met 1-Leu 384
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产品特性
- A DNA sequence encoding the human SPHK1 (Q9NYA1-1)(Met1-Leu384) was expressed the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 116,946.14 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (His tag)
custom-made SPHK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-382) protein (His tag)custom-made SPHK1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (GST tag)SPHK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sphingosine Kinase 1 (SPHK1) (Active) proteinSPHK1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10 % glycerol, pH 8.0
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储存液
- Dithiothreitol (DTT)
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注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1/Sphingosine Kinase 1
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背景
- SPHK,SPHK1,SPK,SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
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分子量
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Calculated MW: 70.3 kDa
Observed MW: 64 kDa
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基因ID
- 8877
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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