SMAD5 蛋白
Quick Overview for SMAD5 蛋白 (ABIN7320167)
抗原
See all SMAD5 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Mouse Smad5 Protein
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序列
- Thr2-Ser465
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产品特性
- A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 186-465) protein (His-IF2DI Tag)
SMAD5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 1-465) protein (GST tag)SMAD5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SMAD, Mothers Against DPP Homolog 5 (SMAD5) protein (GST tag,His tag)SMAD5 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM Nacl,10 % glycerol, pH 8.0
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
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别名
- Smad5
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背景
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Background: SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.
Synonym: 1110051M15Rik,AI451355,Dwf-C,Madh5,MusMLP
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分子量
- 52.2 kDa
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UniProt
- P97454
抗原
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