SMAD5 Protein (AA 2-465) (His-GST)
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Quick Overview for SMAD5 Protein (AA 2-465) (His-GST) (ABIN7320168)
抗原
See all SMAD5 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 2-465
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标记
- This SMAD5 protein is labelled with His-GST.
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原理
- Recombinant Mouse Smad5 Protein (His & GST Tag)
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序列
- Thr2-Ser465
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产品特性
- A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 1-465) protein (GST tag)
SMAD5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 186-465) protein (His-IF2DI Tag)SMAD5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 2-465) proteinSMAD5 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
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别名
- Smad5
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背景
- 1110051M15Rik,AI451355,Dwf-C,Madh5,MusMLP,SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.
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分子量
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Calculated MW: 79.9 kDa
Observed MW: 75-88 kDa
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UniProt
- P97454
抗原
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