SRGN Protein (His-Myc tag)
This Recombinant SRGN protein is expressed in HEK-293 Cells.
产品编号 ABIN7317217
发货至:
中国
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中国
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北京 101111
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Quick Overview for SRGN Protein (His-Myc tag) (ABIN7317217)
抗原
See all SRGN 蛋白
SRGN
(serglycin (SRGN))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
纯度
> 90 % as determined by reducing SDS-PAGE.
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标记
- This SRGN protein is labelled with His-Myc tag.
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原理
- Recombinant Human Serglycin/SRGN Protein (His&Myc Tag)
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序列
- Met 1-Leu158
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产品特性
- A DNA sequence encoding the human SRGN (Met1-Leu158) was fused with the C-terminal polyhistidine-tagged myc at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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serglycin (SRGN) (AA 1-158) protein (GST tag)
SRGN 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB
serglycin (SRGN) protein (His tag)SRGN 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS, WB
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- SRGN (serglycin (SRGN))
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别名
- Serglycin/SRGN
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背景
- PPG,PRG,PRG1,SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
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分子量
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Calculated MW: 17.3 kDa
Observed MW: 27 kDa
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基因ID
- 5552
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UniProt
- P10124
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途径
- Maintenance of Protein Location
抗原
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