s100a4 蛋白
Quick Overview for s100a4 蛋白 (ABIN7197760)
抗原
See all s100a4 (S100A4) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Mouse S100A4 Protein
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序列
- Ala2-Lys101
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产品特性
- A DNA sequence encoding the mouse S100A4 (P07091)(Ala2-Lys101) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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S100 Calcium Binding Protein A4 (S100A4) (AA 1-101) protein (GST tag)
S100A4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
S100 Calcium Binding Protein A4 (S100A4) (Active) proteinS100A4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
S100 Calcium Binding Protein A4 (S100A4) protein (His tag)S100A4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.
S100 Calcium Binding Protein A4 (S100A4) (AA 2-101) protein (Fc Tag)S100A4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
S100 Calcium Binding Protein A4 (S100A4) (AA 1-101) protein (His tag)S100A4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
S100 Calcium Binding Protein A4 (S100A4) protein (Fc Tag)S100A4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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别名
- S100A4
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背景
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Background: S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is necessary for S100A4 to interact with its protein targets and generate biological effects. It can bind the already known targets p53, F-actin, liprin β, myosin heavy chain II, and prevent their phosphorylation and multimerization. It has been demonstrated that S100A4 is directly involved in tumor metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation, and appears to be a metastasis factor and a molecular marker for clinical prognosis. Multiple alternatively spliced variants encoding the same protein have been identified.
Synonym: 18A2,42a,Capl,FSp1,metastasin,Mts1,PeL98,pk9a
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分子量
- 11.7 kDa
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UniProt
- P07091
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途径
- S100 Proteins
抗原
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